Table 3.

Gene expression characterestics.

Symbol	Expr Fold change	findings	Symbol	Expr Fold change	findings
Up-regulatation			Down-regulated
Invasion of tumor
POSTN	286.345	Increases	EDN3	−248.929	Decreases
NRP1	117.774	Increases	VCAN*	−243.495	Increases
IGFBP5*	26.687	Decreases	IL24	−15.763	Decreases
MMP1	20.329	Increases	SERPINE1*	−9.371	Increases
TGFBR2*	6.627	Decreases	SFRP1	−6.729	Decreases
ITGA1	4.868	Increases	MMP2*	−6.046	Increases
TBX2	2.561	Increases	GPC1*	−4.435	Increases
HMGB3*	2.021	Decreases	CEACAM1*	−4.131	Increases
SPHK1	2.012	Increases	EGF*	−3.683	Increases
CTGF*	−2.077	Decreases	CSF1*	−2.879	Increases
Migration of melanoma cell
NRP1*	117.774	Decreases	VCAN	−243.495	Affects
SDC2	11.904	Increases	L1CAM*	−20.041	Increases
TNC	2.217	Increases	SERPINA5*	−10.969	Increases
SPHK1	2.012	Increases	SERPINE1*	−9.371	Increases
			MMP2*	−6.046	Increases
			EGF*	−3.683	Increases
			FN1*	−2.15	Increases
Cell proliferation of tumor cell lines
POSTN	286.345	Increases	PRAME*	−411.078	Increases
SERPINB2*	240.999	Decreases	VCAN*	−243.495	Increases
IL13RA2	191.243	Affects	EMILIN2	−124.892	Decreases
NRP1	117.774	Affects	TRPM2*	−94.449	Increases
HTN1	60.939	Increases	SYNM*	−26.275	Increases
MAF*	50.99	Decreases	PDGFB*	−22.149	Increases
POU4F1	50.781	Increases	L1CAM*	−20.041	Increases
VIP	39.551	Increases	CARD10*	−16.191	Increases
CDK14	30.195	Increases	IL24	−15.763	Decreases
IGFBP5	26.687	Increases	S100A4*	−15.312	Increases
Colony formation
POSTN	286.345	Affects	VCAN*	−243.495	Increases
HTN3*	98.45	Decreases	NUPR1	−31.659	Decreases
VIP	39.551	Increases	PDGFB*	−22.149	Increases
TP63	8.144	Increases	IL24	−15.763	Decreases
CDCA7L	4.871	Increases	S100A4*	−15.312	Increases
ITGA1	4.868	Increases	SERPINE1	−9.371	Decreases
ALDH1A1	4.81	Affects	TBX3*	−7.463	Increases
HAS2	4.155	Increases	DUSP5*	−6.896	Increases
TNC	2.217	Affects	SFRP1*	−6.729	Increases
LIMA1*	2.133	Decreases	PTGES*	−6.519	Increases

*means that the fold changes went the opposite direction compared with previous findings.