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. 2020 Jan 27;10:1220. doi: 10.1038/s41598-020-58134-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The risk of second cancer in different groups based on the full mechanistic dose-response model. A₁, B₁, and C₁ indicate excess absolute risks to the contralateral breast (CB), contralateral lung (CL), and ipsilateral lung (IL), respectively. ^*indicates a statistically significant difference between groups; ^†indicates a significant difference for alternative techniques compared to group 1 (G1) and group 2 (G2). W-TF = 3D-CRT with two tangential fields and wedges; 2F-IMRT = IMRT with two tangential fields; 6F-IMRT = IMRT with six fields; and VMAT = VMAT with double partial arcs.