Fig. 7.

Co-expression of UGGAA₂₂ RNA suppresses TDP-43 aggregation and compound eye degeneration in ALS flies expressing TDP-43 G298S. (a) LM and SEM images of compound eyes of flies expressing TDP-43 G298S mutant, UGGAA22, and TDP-43 G298S mutant with UGGAA22. (b) IHC analyses of eye imaginal discs of TDP-43 G298S flies coexpressing UGGAA22. Reprinted with permission from Neuron, 94(1):108-124.e7, 2017 [22]