Table 3.

How do the KDIGO UOP criteria affect serum creatinine based on a dilutional effect after 24 hours?

KDIGO stage	Metric	Duration	+FB (ml)	Corr [SCr]
1	<0.5 ml/kg/h for 6–12 h	6 h (1,800 + 400 ml In−90 ml Out)	2,100	0.90
		12 h (1,800 + 800 ml In−180 ml Out)	2,420	0.88
2	<0.5 ml/kg/h > 12 h	24 h (1,800 + 1,600 ml In−360 ml Out)	3,040	0.86
3	<0.3 ml/kg/h for 24 h	24 h (1,800 +1,600 ml In−216 ml Out)	3,184	0.85
	OR	12 h (1,800 + 800 ml In−0 ml Out)	2,600	0.87
	Anuria	24 h (1,800 +1,600 ml In−0 ml Out)	3400	0.84

Assumptions for calculations:

1) 30 kg patient with septic shock.

2) 1,800 ml fluid resuscitation (60 ml/kg).

3) 1,600 ml/day standard fluid prescription (BSA metric).

4) Upper limit of KDIGO Urine Output.

5) Volume of distribution of water = 18,000 ml (600 ml/kg).

6) Corrected [SCr] = [(1 mg/dl) × 18,000 ml/(18,000 ml) + fluid balance (FB)].

7) Insensible losses not factored into the calculation since critically ill patients are often intubated and have minimal insensible losses.