TABLE 5.
Diagnosis for MDD |
Diagnosis for DD |
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n cases/n controls | 96/1049 | 188/957 | ||||||||
AUC (95% CI) |
0.915 (0.889–0.941) |
0.846 (0.813–0.880) |
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Cut off | SEN | SPE | J | PPVb | NPV | SEN | SPE | J | PPV | NPV |
MDD optimal cut off a = 23 | 0.833 | 0.868 | 0.701 | 0.365 | 0.983 | 0.649 | 0.899 | 0.548 | 0.557 | 0.929 |
DD optimal cut off = 17 | 0.917 | 0.724 | 0.641 | 0.233 | 0.99 | 0.809 | 0.764 | 0.573 | 0.402 | 0.953 |
BDI-II mild = 14 | 0.938 | 0.636 | 0.574 | 0.191 | 0.991 | 0.830 | 0.670 | 0.5 | 0.331 | 0.953 |
BDI-II moderate = 20 | 0.885 | 0.808 | 0.693 | 0.297 | 0.987 | 0.718 | 0.842 | 0.56 | 0.472 | 0.938 |
BDI-II severe = 29 | 0.656 | 0.937 | 0.593 | 0.488 | 0.968 | 0.484 | 0.960 | 0.444 | 0.705 | 0.905 |
AUC, area under curve; CI, confidence interval; MDD, major depressive disorder; DD, depressive related disorder; SEN, sensitivity; SPE, specificity; J, Youden’s index; PPV, positive predictive value; NPV, negative predictive value. aCut off score with the highest Youden’s index value. bPPV and NPV was calculated based on the prevalence from the research data.