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. 2020 Jan 21;10:3113. doi: 10.3389/fmicb.2019.03113

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Copyright © 2020 Scott, Holden-Dye, O’Connor and Wand.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clearance of P. aeruginosa strains from the C. elegans intestine is highly dependent on intact neuromodulation. The clearance of different strains of P. aeruginosa from the C. elegans intestine in unc-31 (e928) (A) and egl-3 (ok979) (B) mutant worms was measured using methods outlined in Figure 5. These experiments were performed in at least triplicate for all strains. Error bars represent ± SEM. Analysis is by one-way ANOVA with Sidaks multiple comparison. Significance relative to N2 worms is shown. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, ^****P < 0.0001.