Table 1.
Article information and study characteristics of 12 heat acclimation studies included in the meta-analysis
| Author and year | Sample size | Population | HA protocol | Control | Outcome measure |
|---|---|---|---|---|---|
| Amorim (2011) | 9 total (7 male, 2 female) | Physically active (age 25 ± 3) | 10 sessions within 14 day period. 100 min/session (42 °C; 30% RH; WB:25.9 ± 0.4°), 56% VO2peak | NA | Pre-/post-PBMC HSP72 protein |
| Gibson (2015a) (Scan Med Sci) | 24 males | Physically active (age 26 ± 5) |
Group 1: 10 sessions, 90 min (40 °C; 39 ± 7.8%RH), 50% VO2peak (n = 8). Group 2: 10 sessions, 90 min (40 °C; 39 ± 7.8% RH), 65% VO2peak, controlled core temp at 38.5–39 °C (n = 8) |
NA | Pre-/post-leukocyte HSP72 mRNA. |
| Gibson (2015b) (JAP) | 16 males | Physically active (age 22 ± 4) | 10 sessions, 90 min (40 °C; 40% RH), 65% VO2peak (n = 8), controlled core temp ≥ 38.5 | Exercise matched control, 20 °C (n = 8) | Pre-/post-leukocyte HSP72 mRNA. |
| Hom (2012) | 11 males | Healthy (20 ± 1) | 11 sessions, 90 min (33 °C; 30–50% RH), 50% VO2max | NA | Pre-/post-monocyte HSP72 protein |
| Kuennen (2011) | 8 men | Healthy (28 ± 1) | 7 sessions, 100 min (46.5 °C; 20% RH) | NA | Pre-/post-PBMC HSP70 protein |
| Lee (2015) | 16 males | Healthy (22 ± 4) | 3 sessions, 60 min (40 °C; 20% RH), 50% VO2peak (n = 8) | Exercise matched control, 20 °C (n = 8) | Pre-/post-monocyte HSP72 protein |
| Lee (2016) | 7 males | Physically fit (25 ± 5) | 10 session, 60 min (40 °C; 25% RH), 50% VO2peak | NA | Pre-/post-monocyte HSP72 protein |
| Magalhães (2010) | 9 males | Healthy (25 ± 1) | 11 sessions, 60 min (40 °C; 45% RH). | NA | Pre-/post-leukocytes HSP72 protein |
| Marshall (2007) | 7 males | Healthy (30 ± 4) | 3 sessions, 120 min (38 °C; 60% RH) 38% VO2peak | NA |
Pre-/post-PBMC HSP72 mRNA Pre-/post-PBMC HSP72 protein |
| McClung (2007) | 6 total (male and female numbers not reported) | Healthy soldiers (23) | 10 sessions, 100 min (49 °C; 20% RH) | NA | Pre-/post-PBMC HSP72 |
| Watkins (2008) | 10 males | Physically active (23 ± 3) | 7 sessions, 30 min (39.5 °C; 27% RH), 75% VO2peak | NA | Pre-/post-skeletal muscle HSP72 |
| Yamada (2007) | 12 total (10 males, 2 females) | Healthy (24 ± 4) | 10 sessions, 100 min (42.5°; 27.9% RH; WB: 25.9 ± 0.4°), 56% VO2max | NA | Pre-/post-PBMC HSP72 |
RH: relative humidity, PBMC: peripheral blood mononuclear cells, VO2peak: peak oxygen consumption, VO2max: maximal oxygen consumption