Table 3.
Pharmacokinetic parameters calculated by using “PK solver 2.0” dose | T½ (h) | Tmax (h) | Cmax (CPM/g) | AUC (h*CPM/g) |
---|---|---|---|---|
5 mg/kg | 6.3 | 0.5 | 546,975.5 | 6,481,488.8 |
1 mg/kg | 6.4 | 1.0 | 109,019.8 | 1,233,026.6 |
0.25 mg/kg | 6.9 | 1.0 | 26,623.8 | 297,516.5 |