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The effect of urolithin A on SIRT1/p53 signaling in the hippocampus tissue of d-gal-induced aging mice (A). Urolithin A attenuated the excessive apoptosis in the hippocampus tissue of d-gal-induced aging mice (B). Data are presented as mean ± S.D. from each group (n = 12). #P < 0.05 and ##P < 0.01 versus the control group; *P < 0.05 and **P < 0.01 versus the model group
