Table 3.

Hemodynamic changes with respiratory impedance

	6 cm H2O	p value	12 cm H2O	p value
CBF, blood flow index	+ 2.9% (− 5.0 to + 17.6)	0.19	+ 0.5% (− 2.1 to + 13.5)	0.14
MCAv, cm/s	+ 2.3 cm/s (3.8%) (− 4.6 to + 9.4)	0.19	+ 4.8 cm/s (7.3%) (+ 2.6 to + 17.1)	0.004
MAP	+ 4.8 mmHg (4.1%) (+ 1.2 to + 10.4)	0.013	+ 5.1 mmHg (4.4%) (+ 1.0 to + 7.8)	0.017
HR	+ 1.6 beats/min (1.9%) (+ 0.25 to + 3.0)	0.06	+ 1.9 beats/min (2.2%) (− 0.41 to + 3.5)	0.021
End-tidal CO2	+ 0.036 mmHg (0.1%) (− 1.7 to + 0.57)	0.69	− 0.71 mmHg (2.0%) (− 3.2 to + 1.2)	0.44
Cardiac output	+ 0.065 L/min (1.0%) (− .13 to + 0.29)	0.22	+ 0.31 L/min (4.1%) (− 0.22 to + 0.52)	0.22

All reported values are changes in median (IQR). Change in median is reported as absolute value and % relative to baseline period immediately preceding RI. Blood flow index as measured by DCS is only reported as % change. p values were calculated by Wilcoxon signed ranks tests, in comparison to baseline values