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Salmonella SiiE suppresses the retention of IgG-secreting plasma cells in BM survival niches by competing with laminin β1. SiiE secreted by Salmonella competes with laminin β1 to interact with integrin β1. The competition induces the detachment and then deletion of IgG-secreting plasma cells from laminin β1+CXCL12+ survival niches of the BM.
