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. 2020 Jan 21;10:1535. doi: 10.3389/fphys.2019.01535

FIGURE 1.

FIGURE 1

In vivo left ventricular hemodynamic function in WT and GAMT–/– mice at 18 months of age (A) GAMT–/– mice have lower body weight throughout their life. (B) Heart rate, (C) LV systolic pressure (LVSP), (D) LV end-diastolic pressure (LVEDP), (E) maximal rate of pressure rise (dP/dtmax) as a measure of contractility, and (F) time constant of isovolumetric relaxation (tau). N = 12 (5F/7M) per genotype, ∗∗denotes P < 0.01, ∗∗∗∗P < 0.0001 for WT versus KO at the same age by unpaired t-test (A–D,F) and Welch’s t-test (E). All values are mean ± SEM.