FIGURE 5.

Mesenteric artery reactivity. (A,B) Contractile responses to phenylephrine (PE) and (C,D) relaxation responses to acetylcholine (ACh) in mesenteric arteries from control and LPS-induced SIRS (LPS) mice treated with (A,C) vehicle or glucosamine (GlcN) and (B,D) vehicle or thiamet-G (ThG). Data are expressed as mean ± SEM of contraction and relaxation values and are representative of 4–5 experiments. Cont, vehicle-treated control mice; LPS, LPS (20 mg/Kg i.P.)-treated mice; Cont + GlcN and LPS + GlcN, mice treated with glucosamine (GlcN); Cont + ThG and LPS + ThG, mice treated with thiamet-G (ThG). ^∗p < 0.05 vs. respective control; ^#p < 0.05 vs. LPS. ANOVA followed by Bonferroni’s post-test.