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Circadian regulator BMAL1 is closely correlated with the development of MCC. A, qRT‐PCR analysis showed the mRNA levels of Bmal1, Per1, Clock, Cry1, Cry2 and Rev‐erbα at indicated time in cartilages of 4‐, 8‐, 10‐ and 12‐week‐old mice (n = 3 for each bar). B, C, Western blot analysis showed the protein levels of BMAL1 and CLOCK in the mandibular condyle cartilages at Zeitgeber time 10 (ZT10) (n = 3 independent experiments)
