Figure 3.

KCs from CCL4‐induced liver fibrosis have a pro‐fibrotic phenotype. A‐D, Mannose receptor, interleukin‐10 (IL‐10), Ym1 and transforming growth factor β1 (TGF‐β1) mRNAs in KCs were measured by quantitative PCR (n = 3 mice/ group). E, F, The α‐SMA expression of HSCs cultured in KCs supernatant from olive‐induced and CCL4‐induced mice with or without TIM‐4 interference was determined by immunoblot and quantitative analysis. G, H, Fibronectin and collagen 1α mRNAs in HSCs cultured in KC supernatant from olive‐induced and CCL4‐induced mice with or without TIM‐4 interference was measured by quantitative PCR. *P < .05; ***P < .0001. Values represent the mean ± SD of at least three independent experiments