Table 1.
Genotype | Number of progenies | ||
---|---|---|---|
♀ Rbm14 +/+ × ♂ Rbm14 +/− | ♀ Rbm14 +/− × ♂ Rbm14 +/+ | ♀ Rbm14 +/− × ♂ Rbm14 +/− | |
Rbm14 +/+ | 65 (46.1%) | 69 (51.5%) | 51 (32.9%) |
Rbm14± | 76 (53.9%) | 65 (48.5%) | 104 (67.1%) |
Rbm14 −/− | 0 | 0 | 0 |
Mendelian ratio | 1:1:0 | 1:1:0 | 1:2:1 |
Quantification of pups with different genotypes by three different mating strategies: ♀ Rbm14 +/+ × ♂ Rbm14 +/−; ♀ Rbm14 +/− × ♂ Rbm14 +/+ and ♀ Rbm14 +/− × ♂ Rbm14 +/−. No Rbm14−/− pups were produced by interbreeding of Rbm14 +/− male and female mice, indicating that homozygous deletion of Rbm14 +/− results in embryonic lethality. More than 10 litters of pups were genotyped and quantified in each group (for ♀ Rbm14 +/+ × ♂ Rbm14 +/−, n = 141; for ♀ Rbm14 +/− × ♂ Rbm14 +/+, n = 134 and for ♀ Rbm14 +/− × ♂ Rbm14 +/−, n = 155).