Table 2.
The involvement of SNHG15 in multiple signalling pathways
| Cancer type | Cell lines | Expression | Role | Related genes | Signalling pathways |
|---|---|---|---|---|---|
| Colorectal cancer | CaCO‐2, HCT‐116 | Upregulated | Oncogenic | Wnt1, C‐Myc, Cyclin‐D1, β‐catenin, E‐cadherin, N‐cadherin, Vimentin, Snail | WNT/β‐catenin pathway |
| Renal cell carcinoma | ACHN, 786‐O | Upregulated | Oncogenic | NF‐kb, Snail1, Slug, ZEB1, N‐cadherin, Vimentin, E‐cadherin | NF‐kb signalling pathway |
| Gastric cancer | MGC803, BGC823 | Upregulated | Oncogenic | MMP2, MMP9 | EMT regulation |
| Lung cancer | A549 | Upregulated | Oncogenic | MMP2, MMP9, E‐cadherin, N‐cadherin, Vimentin | EMT regulation |
| Colorectal cancer | HCT116, SW480,SW1116 | Upregulated | Oncogenic | Slug, E‐cadherin | EMT regulation |
| Thyroid cancer | BCPAP, K1 | Upregulated | Oncogenic | YAP1, MST1, LATS1 | YAP‐Hippo pathway |