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. 2019 Oct 30;53(1):e12700. doi: 10.1111/cpr.12700

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© 2019 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Silencing CHD1 inhibits cell proliferation and induces apoptosis in glioma cells. A, Kaplan‐Meier curve of the correlation between CHD1 expression and overall survival (OS) in patients with glioma. B, qRT‐PCR results of MATN1‐AS1 and CHD1 expression after CHD1 downregulation in U87 and U251 cells. C‐D, Cell proliferative ability of U87 and U251 cells was evaluated by MTT assay and colony formation assay. E, Depletion of CHD1 enhanced cell apoptosis in glioma cells. ^** P < .01 compared with controls. N.S: no significance