FIG 1.

Phylogenetic analysis of the gyrA quinolone resistance-determining region of the Neisseria isolates and genomes. Phylogenetic analysis of the nucleotide sequences of 263 gyrA alleles (nucleotides 115 to 639) from N. meningitidis (n = 12,771), N. gonorrhoeae (n = 4,118), N. lactamica (n = 562), N. subflava (n = 30), N. cinerea (n = 21), N. mucosa (n = 22), and other commensal Neisseria (n = 63) isolates and genomes collected in this study and from the Neisseria PubMLST database was conducted with the MEGA (version 5) program using the unweighted pair group method with arithmetic mean averages (UPGMA). Clusters were identified if bootstrap values were >70% in the bootstrap test with 1,000 replicates.