FIG 1.

Subject disposition. The ITT analysis set included all randomized subjects who received the challenge virus and at least one dose of study drug. The ITT-I analysis set included all randomized subjects who received challenge virus and at least one dose of study drug and met the criterion for laboratory-confirmed RSV infection (presence of viral shedding). The ITT-A analysis set was a subset of the ITT-I population that included subjects in whom RSV infection was confirmed before administration of study drug. One subject assigned to RV521 350 mg withdrew consent following three doses. ITT, intent-to-treat; ITT-I, intent-to-treat infected; ITT-A, intent-to-treat infected A; RSV, respiratory syncytial virus.