TABLE 1.
Distribution of GSK656 MICs among M. tuberculosis isolates
| Classification | No. of strains with MIC (mg/liter) of: |
Total no. | MIC50 (mg/liter)a | MIC90 (mg/liter) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| <0.008 | 0.008 | 0.016 | 0.031 | 0.063 | 0.125 | 0.25 | 0.5 | 1.0 | 2.0 | 4.0 | 8.0 | >8.0 | ||||
| Non-MDR | 1 | 3 | 9 | 6 | 16 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 40 | 0.063 | 0.125 |
| MDR | 0 | 2 | 4 | 6 | 14 | 8 | 4 | 1 | 0 | 1 | 0 | 0 | 0 | 40 | 0.063 | 0.25 |
| XDR | 0 | 0 | 3 | 4 | 9 | 5 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 25 | 0.063 | 0.5 |
| Total | 1 | 5 | 16 | 16 | 39 | 17 | 6 | 2 | 0 | 2 | 0 | 1 | 0 | 105 | 0.063 | 0.25 |
a
MIC50, concentration required to inhibit the growth of 50% of the isolates tested; MIC90, concentration required to inhibit the growth of 90% of the isolates tested.