TABLE 2.
Antimicrobial susceptibility data for the 243 isolates of P. aeruginosa causing bloodstream infections
| No. of isolates susceptible to the indicated antibiotic (MIC [mg/liter]) (%)a: |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Isolate type (no.)b | PIP/TZ (≤16) | CAZ (≤8) | FEP (≤8) | ATM (≤16) | IMP (≤4) | MER (≤2) | GEN (≤4) | TOB (≤4) | AMI (≤8) | CIP (≤0.5) | COL (≤2) | TOL/TZ (≤4) | CAZ/AVI (≤8) |
| All (243) | 154 (63.4) | 152 (62.6) | 152 (62.6) | 26 (10.7) | 144 (59.3) | 144 (59.3) | 157 (64.6) | 163 (67.1) | 205 (84.4) | 133 (54.7) | 243 (100) | 10 (11.2) | 43 (49.4) |
| MDR (93) | |||||||||||||
| Non-XDR (6) | 2 (33.3) | 2 (33.3) | 2 (33.3) | 0 (0) | 4 (66.7) | 5 (91.7) | 5 (91.7) | 5 (91.7) | 6 (100) | 4 (66.7) | 6 (100) | ND | ND |
| XDR (87) | 2 (2.2) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 4 (4.5) | 9 (10.1) | 49 (56.3) | 0 (0) | 87 (100) | 10 (11.2) | 43 (49.4) |
| VIM-2/ST175 (43) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 43 (100) | 0 (0) | 43 (100) | 0 (0) | 0 (0) |
| GES-5/ST235 (33) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 33 (100) | 0 (0) | 33 (100) |
| Othersc (11) | 2 (18.2) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 4 (36.4) | 9 (81.8) | 6 (54.5) | 0 (0) | 11 (100) | 10 (90.9) | 10 (90.9) |
| Non-MDR (150) | |||||||||||||
| ModR (127) | 127 (100) | 127 (100) | 127 (100) | 3 (2.3) | 117 (92.2) | 116 (91.3) | 125 (98.4) | 126 (99.2) | 127 (100) | 106 (83.4) | 127 (100) | ND | ND |
| MultiS (23) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | 23 (100) | ND | ND |
a
PIP/TZ, piperacillin-tazobactam; CAZ, ceftazidime; FEP, cefepime; ATM, aztreonam; IMP, imipenem; MER, meropenem; GEN, gentamicin; TOB, tobramycin; AMI, amikacin; CIP, ciprofloxacin; COL, colistin; TOL/TZ, ceftolozane-tazobactam; CAZ/AVI, ceftazidime-avibactam; ND, not done.
b
MDR, multidrug resistant; XDR, extensively drug resistant; ModR, moderately resistant; MultiS, multidrug susceptible; ST, sequence type.
c
Eleven extensively drug-resistant P. aeruginosa isolates had no carbapenemase genes (blaGES, blaVIM, or blaIMP) identified.