TABLE 4.

Multivariate analysis of predictor factors for 5-day and 30-day crude mortality of patients with P. aeruginosa bloodstream infections.

Variableb	5-day mortality (early mortality)a,c						30-day mortality (late mortality)c
	Model 1		Model 2		Model 3		Model 1		Model 2
	aOR (CI 95%)	P	aOR (CI 95%)	P	aOR (CI 95%)	P	aOR (CI 95%)	P	aOR (CI 95%)	P
Severe neutropenia	9.47 (3.52–25.5)	<0.001	6.57 (2.62–16.5)	<0.001	9.21 (3.40–24.9)	<0.001	2.97 (1.38–6.35)	0.005	2.80 (1.32–5.92)	0.007
Respiratory infection	3.22 (2.02–5.14)	<0.001	2.94 (1.87–4.62)	<0.001	3.23 (2.01–5.16)	<0.001	1.93 (1.30–2.86)	0.001	1.95 (1.31–2.90)	0.001
Nosocomial acquisition	__	__	__	__	__	__	1.62 (1.10–2.37)	0.012	1.56 (1.07–2.27)	0.019
Pitt score ≥2	2.49 (1.39–4.44)	0.002	2.14 (1.23–3.71)	0.007	2.42 (1.34–4.36)	0.003	1.86 (1.28–2.70)	0.001	1.81 (1.25–2.63)	0.002
exoU+/exoS− genotype	2.99 (1.06–8.42)	0.038	3.58 (1.31–9.79)	0.013			3.89 (1.65–9.19)	0.002
O11 serotype					3.64 (1.20–11.1)	0.022			3.63 (1.42–9.31)	0.007
MDR phenotype			2.39 (0.97–5.87)	0.057			2.18 (1.04–4.58)	0.04	2.17 (1.03–4.58)	0.042
Inadequate empiric antibiotic	4.57 (1.59–13.1)	0.005			4.17 (1.42–12.2)	0.009	__	__	__	__
Median TTP (hours) of blood culture (IQR)d	0.88 (0.80–0.97)	0.009	0.90 (0.82–0.98)	0.014	0.88 (0.81–0.97)	0.01	0.91 (0.86–0.97)	0.005	0.92 (0.86–0.97)	0.008

^aaOR, adjusted odds ratio; CI, confidence interval.

^bMDR, multidrug-resistant; TTP, time to positivity; —, variables included in the initial model of multivariate analysis, then discarded in a stepwise backward selection process.

^cThree patients were excluded from analysis due to palliative treatment, thus the total was n = 240.

^dTime from the start of incubation to the alert signal in the blood culture system.