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Representative data traces. Subjects breathed room air (21% O2, normoxia) and then quietly switched to 100% O2 to experimentally “turn off” the carotid chemoreceptors. Because of the acute effects of hyperoxia on the carotid chemoreceptors, data were analyzed from the first 1 min of hyperoxia exposure and compared with data from the first min of normoxia immediately preceding the exposure. MSNA, muscle sympathetic nerve activity; au, arbitrary units.
