Table 4.
Effect of acute hyperoxia and low-dose dopamine at baseline and during hyperinsulinemia
| Normoxia + DA | Hyperoxia + DA | |
|---|---|---|
| Heart rate, beats/min | ||
| Baseline | 63 ± 1 | 62 ± 1† |
| Hyperinsulinemia | 66 ± 2 | 64 ± 2† |
| Mean blood pressure, mmHg | ||
| Baseline | 97 ± 2 | 96 ± 2 |
| Hyperinsulinemia | 95 ± 2 | 95 ± 2 |
| Tidal volume, L/breath | ||
| Baseline | 469 ± 40 | 542 ± 84 |
| Hyperinsulinemia | 527 ± 39 | 567 ± 75 |
| Breathing frequency, breaths/min | ||
| Baseline | 14.3 ± 0.7 | 13.9 ± 0.8 |
| Hyperinsulinemia | 13.6 ± 1.2 | 13.8 ± 1.1 |
| Minute ventilation, L/min | ||
| Baseline | 6.5 ± 0.4 | 7.1 ± 0.7 |
| Hyperinsulinemia | 6.8 ± 0.4 | 7.2 ± 0.6 |
| Inspired O2, % | ||
| Baseline | 21 ± 1 | 84 ± 2† |
| Hyperinsulinemia | 21 ± 1 | 86 ± 2† |
Values are means ± SE; n = 10 (5 male/5 female). DA, dopamine. Data were analyzed by 2-way repeated-measures ANOVA, normality test (Shapiro-Wilk), equal variance test, and pairwise multiple comparison (Student-Newman-Keuls method):
†
P < 0.05 vs. normoxia + DA.