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Vascular conductance in response to increasing doses of serotonin in healthy adults [HA, n = 12 (8 women); open symbols] and in those with major depressive disorder [MDD, n = 12 (8 women); filled symbols]. Microvascular responsiveness to serotonin was preserved in MDD (P = 0.09). CVCmax, maximal cutaneous vascular conductance. Data are means ± SE and were analyzed using two-way repeated-measures ANOVA.
