Fig. 3.

Effect of 10⁻⁸ mol/L angiotensin II (ANG II) on $O_2^{-}$ production by proximal tubule suspensions from control rats and rats that consumed 20% fructose (FRUC) for 6–8 days in the presence of GKT136901, a NADPH oxidase 1/4 inhibitor. A: basal and ANG II-stimulated $O_2^{-}$ production. B: ANG II-induced $O_2^{-}$ production. RLU, relative light units. n = 5 for each group.