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Morphological characteristics of TA muscle fibers from WT, Krt18-KO, and Krt18-DN mice
| Genotype | n | CNF, % | Slow Fibers, % | Average Fiber Size, μm | Variance, % |
|---|---|---|---|---|---|
| WT FVB | 4 | 1.2 ± 0.26 | 1.2 ± 0.34 | 36.6 ± 9.4 | 25.7 |
| K18-KO | 3 | 1.4 ± 0.23 | 6.3 ± 4 | 36.6 ± 10.8 | 29.5 |
| K18-DN | 3 | 1.0 ± 0.21 | 5.9 ± 2.4 | 27.7 ± 8.9 | 32.1 |
Values are means ± SD. No significant differences were found (analyzed with VassarStats). CNF, centrally nucleated fibers; DN, dominant negative; KO, knockout; TA, tibialis anterior; WT, wild type.
