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A: esophagogastric junction (EGJ) pressure before Botox (1), at 2 wk (2), and at 6 mo (3) after Botox injection. Note reduction in the EGJ pressure and reflux with deep inspiration at 2 wk and return of EGJ pressure at 6 mo. B: EGJ pressure during Müller’s maneuver, straight leg raise, and sniffing, 2 wk (1–3) and 6 mo (4–6) after the Botox injection. Note return of EGJ pressure and absence of reflux during the maneuvers at 6 mo. UES, upper esophageal sphincter.
