Fig. 6.
Expression of hepatic and kidney genes involved in bile acid synthesis and transport. Term piglets were administered lipid emulsions for 14 days containing standard soy oil (SO) emulsion (IL), α-tocopherol-supplemented SO (VITE), or SO supplemented with daily injections of 10 mg·kg−1·day−1 Rifadin IV (RIF). Quantitative PCR analysis of hepatic genes associated with bile acid transport (A), bile acid synthesis (B), and phospholipid and xenobiotic clearance (C) was performed. Kidney genes associated with bile acid transport (D) are also shown. All gene expression was normalized to β-actin. Enteral control piglet historical mean values, when available, are represented by the dashed line. Values are expressed as means ± SE. One-way ANOVA; n = 5–7 piglets/group.