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. 2019 Nov 6;123(1):4–21. doi: 10.1152/jn.00347.2019

Fig. 7.

Fig. 7.

Organization and projections of various classes of commissural interneuron (CIN) according to embryological origin. Glutamatergic dI5 cells settle in the deep dorsal horn (DH) and project to the contralateral dorsal horn. Their target neurons are unknown. V0D cells are inhibitory. They settle within the intermediate gray matter (IZ) or ventral horn (VH) and project to motoneurons (Mn). V0C are cholinergic and found in lamina X and VII close to the midline. Some of them project bilaterally to contralateral and ipsilateral motoneurons and may have additional projections to Renshaw cells (RCs). V0V cells are excitatory and project to motoneurons and Ia inhibitory interneurons (Ia INs). V3 cells are excitatory and have bilateral projections to ipsilateral and contralateral motoneurons. Inhibitory dI6 cells are present in laminae VII and VIII. They project to contralateral motoneurons and additional ventral horn cells. Green, excitatory cells; red, inhibitory cells; orange, cholinergic cells. Co, contralateral; I, ipsilateral. Based on data from Alaynick et al. (2011); Briscoe et al. (1999); Kiehn (2016); Vallstedt and Kullander (2013); Zagoraiou et al. (2009).