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. 2019 Nov 6;123(1):4–21. doi: 10.1152/jn.00347.2019

Table 2.

Embryological origin of commissural interneurons

Cell Type Location Projection Transmitter Transcription Factor Contralateral Terminations Action References
dI5 VI contralateral Glutamate Lmx1b dorsal horn ? Lu et al. (2015); Vallstedt and Kullander (2013)
dI6 VII–VIII contralateral GABA/glycine Dmrt3 VII–IX, MN Control of gait Andersson et al. (2012); Dyck et al. (2012)
V0D VII–VIII contralateral GABA/glycine Dbx1 VII–IX, MN Coordination of left–right alternation at low speed Talpalar et al. (2013)
V0V VII–VIII contralateral Glutamate Dbx1 VII–VIII Coordination of left–right alternation at high speed Talpalar et al. (2013)
V0C VII, X contralateral/bilateral Acetylcholine Dbx1 IX, VII, MN Modulation of motoneuron firing frequency Stepien et al. (2010); Zagoraiou et al. (2009)
V3 VII contralateral/bilateral Glutamate Nkx2.2 VII–IX, MN Control of rhythmicity Briscoe et al. 1999); Zhang et al. (2008)

Roman numerals refer to laminae of Rexed. MN, contacts on contralateral motoneurons; ?, unknown action.