Fig. 7.

Epilepsy-related changes in parvalbumin (PV)-immunoreactive bouton densities and spatial distribution. A and B: the spatial distribution of total PV+ bouton density per neuron is represented by mapping the density value in each imaging field to its location on the montage image for a control subject (A) and his age- and sex-matched sclerotic subject (B). C and D: boxplots represent PV basket cells (C) and PV chandelier cells (D) bouton density across the diagnosis groups based on the average of all imaging sites per subject with the central mark representing the mean in each group, and tails represent the 99th confidence interval; a.u. = arbitrary unit. Each diagnosis group was assigned a color: red: sclerosis; blue: nonsclerosis; black: control. *P < 0.05, significant interactions in post hoc analysis. ⁺Outlier values.