Fig. 6.

Dust extract (DE) inhibits and amphiregulin (AREG) promotes recellularization of human lung scaffold matrixes by human lung fibroblasts (HLF). Denuded human lung mesenchymal scaffolds were seeded with human primary lung fibroblasts and cultured for 5 days (A). Scaffold cultures were treated with medium alone (control), DE, and/or AREG on day 1. Recellularization of the scaffold cultures was assessed by MTT uptake and formazan crystal formation on day 5 (B). Each symbol represents one scaffold culture (n = 16 scaffolds per condition). *P < 0.05; §P < 0.001, by ANOVA.