Table 2. Multivariable-adjusted OR and 95% CI for the association of social jetlag with depressive symptoms

	Social jetlag
	<1 h	1 to <2 h	≥ 2 h	P-value for trend*
CES-D (≥16)
Cases/number of subjects	238/892	132/399	52/113
Model 1†	1.00 (reference)	1.29 (1.00 to 1.68)	2.13 (1.41 to 3.20)	<0.001
Model 2‡	1.00 (reference)	1.33 (0.98 to 1.81)	2.32 (1.39 to 3.87)	0.002
Model 3§	1.00 (reference)	1.30 (0.95 to 1.78)	2.14 (1.26 to 3.62)	0.01

Values in bold show statistical significance.

*Based on multivariable logistic regression analysis with assignment of ordinal numbers to each category of social jetlag.

^†Model 1 adjusted for age (year, continuous), sex, and site.

^‡Model 2 additionally adjusted for job (white-collar or blue-collar worker), job grade (low or middle and high), married (yes or no), overtime work (<10, 10–29, or ≥30 h/mo), smoking status (never-smoked, former smoker, current smoker smoking <20 cigarettes/d, or current smoker smoking ≥20 cigarettes/d), alcohol consumption (nondrinker including infrequent drinker consuming alcohol less than once per week, drinker consuming <23 g of ethanol/d, drinker consuming ≥23 to <46 g of ethanol/d, or drinker consuming ≥46 g of ethanol/d), BMI (kg/m², continuous), average sleep duration on weekdays and on the weekend (hours/day, continuous), sleep quality (good, very good, not so good, or bad), flexible work (yes or no), and chronotype (hours, continuous).

^§Model 3 additionally adjusted for physical activity at work (<3, 3 to <7, 7 to <20, or ≥20 METs-h/d), leisure-time physical activities (0, 0 to <3, 3 to <10, or ≥10 METs-h/wk), energy intake (kcal/day, continuous), intake of magnesium (mg/1,000 kcal, continuous), calcium (mg/1,000 kcal, continuous), iron (mg/1,000 kcal, continuous), zinc (mg/1,000 kcal, continuous), folate (µg/1,000 kcal, continuous), vitamin C (mg/1,000 kcal, continuous), vitamin B₆ (mg/1,000 kcal, continuous), vitamin B₁₂ (µg/1,000 kcal, continuous), and ω-3 PUFA (% energy, continuous).