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. 2020 Jan 27;8(1):2325967119893920. doi: 10.1177/2325967119893920

TABLE 5.

Change in Patient-Reported Outcome Measure Scores From Baseline to 5 Years by Mechanical Symptomsa

Surgery Nonsurgery Between-Group Difference
KOOSPAIN
 No mechanical symptoms
  n 20 15
  Mean (95% CI) 36.6 (28.4 to 44.7) 26.9 (17.4 to 36.4) 9.7 (–3.1 to 22.4)
  P value .136
 Mechanical symptoms
  n 45 19
  Mean (95% CI) 18.2 (12.8 to 23.5) 27.5 (19.3 to 35.7) –9.3 (–19.2 to 0.5)
  P value .063
 Within-group difference
  Mean (95% CI) 18.4 (8.7 to 28.1) –0.6 (–13.0 to 11.9)
  P value <.001 .925
KOOSSYMPTOMS
 No mechanical symptoms
  n 19 16
  Mean (95% CI) 25.1 (17.3 to 33.0) 20.6 (11.7 to 29.4) 4.6 (–7.2 to 16.4)
  P value .445
 Mechanical symptoms
  n 46 19
  Mean (95% CI) 13.1 (8.0 to 18.2) 24.2 (16.4 to 32.1) –11.1 (–20.5 to –1.8)
  P value .020
 Within-group difference
  Mean (95% CI) 12.1 (2.7 to 21.4) –3.6 (–15.6 to 8.3)
  P value .012 .545
KOOSADL
 No mechanical symptoms
  n 20 16
  Mean (95% CI) 28.3 (21.1 to 35.5) 17.1 (9.0 to 25.2) 11.2 (0.1 to 22.3)
  P value .049
 Mechanical symptoms
  n 44 18
  Mean (95% CI) 14.1 (9.4 to 18.8) 19.8 (12.4 to 27.2) –5.7 (–14.5 to 3.1)
  P value .199
 Within-group difference
  Mean (95% CI) 14.2 (5.6 to 22.8) –2.7 (–13.6 to 8.2)
  P value .001 .622
KOOSSPORTS
 No mechanical symptoms
  n 20 14
  Mean (95% CI) 37.6 (25.5 to 49.8) 32.4 (17.0 to 47.8) 5.2 (–15.1 to 25.5)
  P value .611
 Mechanical symptoms
  n 45 19
  Mean (95% CI) 24.5 (16.5 to 32.5) 27.9 (15.7 to 40.2) –3.4 (–18.1 to 11.2)
  P value .641
 Within-group difference
  Mean (95% CI) 13.1 (–1.3 to 27.6) 4.5 (–15.2 to 24.1)
  P value .073 .652
KOOSQoL
 No mechanical symptoms
  n 20 15
  Mean (95% CI) 41.6 (31.1 to 51.1) 31.5 (19.0 to 43.9) 10.2 (–6.5 to 26.8)
  P value .229
 Mechanical symptoms
  n 45 19
  Mean (95% CI) 27.4 (20.5 to 34.3) 31.3 (20.6 to 41.9) –3.9 (–16.6 to 8.8)
  P value .547
 Within-group difference
  Mean (95% CI) 14.2 (1.8 to 26.7) 0.2 (–16.0 to 16.5)
  P value .026 .978
EQ-5D
 No mechanical symptoms
  n 19 15
  Mean (95% CI) 0.23 (0.15 to 0.31) 0.22 (0.13 to 0.32) 0.01 (–0.12 to 0.14)
  P value .886
 Mechanical symptoms
  n 45 19
  Mean (95% CI) 0.17 (0.12 to 0.23) 0.24 (0.15 to 0.32) –0.07 (–0.17 to 0.04)
  P value .201
 Within-group difference
  Mean (95% CI) 0.06 (–0.04 to 0.16) –0.02 (–0.14 to 0.11)
  P value .239 .819
EQ-VAS
 No mechanical symptoms
  n 19 14
  Mean (95% CI) 21.2 (15.1 to 27.3) 20.3 (13.2 to 27.4) 0.9 (–8.5 to 10.3)
  P value .846
 Mechanical symptoms
  n 44 18
  Mean (95% CI) 15.6 (11.6 to 19.6) 18.9 (12.6 to 25.3) –3.3 (–10.8 to 4.2)
  P value .385
 Within-group difference
  Mean (95% CI) 5.6 (–1.7 to 12.9) 1.3 (–8.2 to 10.9)
  P value .133 .779

aBolded values indicate statistical significance (P < .05). Adjusted for overall mean scores at baseline. ADL, activities of daily living; EQ-5D, EuroQol 5 dimensions; EQ-VAS, EuroQol visual analog scale; KOOS, Knee injury and Osteoarthritis Outcome Score; QoL, quality of life.