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. 2020 Jan 28;21:30. doi: 10.1186/s12931-020-1297-2

Table 2.

Correlation of clinical variables and phagocytosis-associated receptor expression on alveolar macrophages (univariable analysis)

FcγRI MSR-1 Siglec-1
MFI ratio % positive MFI % positive MFI % positive
Age rs 0.2735 0.1550 0.1842 0.1776 0.3462 0.3061
P value 0.1365 0.4051 0.3213 0.3392 0.0564 0.0940
Gender rs −0.2666 −0.3258 − 0.1852 − 0.2889 −0.3184 −0.3184
P value 0.0737 0.3185 0.1149 0.0809 0.0809 0.0737
Smoking history (Pack-years) rs −0.3670 − 0.3645 − 0.3568 − 0.3817 − 0.5333 − 0.4753
P value 0.0423 0.0438 0.0488 0.0341 0.0020 0.0069
FEV1 (% pred) rs 0.4140 0.3533 0.5115 0.4459 0.4656 0.3958
P value 0.0206 0.0512 0.0033 0.0119 0.0083 0.0275
Low attenuation area scores rs −0.5358 −0.5577 −0.4564 −0.4945 −0.6778 −0.6440
P value 0.0019 0.0011 0.0099 0.0047 < 0.0001 < 0.0001

Bold denotes values P < 0.05

rs, Spearman rank correlation coefficient. FEV1, forced expiratory volume in 1 second. MFI, mean fluorescence intensity

MFI ratio indicates the ratio of receptor MFI to the corresponding FMO control MFI

% positive indicates the percentage of a receptor-positive alveolar macrophages to total alveolar macrophages