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. 2020 Jan 28;21:30. doi: 10.1186/s12931-020-1297-2

Table 2.

Correlation of clinical variables and phagocytosis-associated receptor expression on alveolar macrophages (univariable analysis)

		FcγRI		MSR-1		Siglec-1
		MFI ratio	% positive	MFI	% positive	MFI	% positive
Age	r_s	0.2735	0.1550	0.1842	0.1776	0.3462	0.3061
Age	P value	0.1365	0.4051	0.3213	0.3392	0.0564	0.0940
Gender	r_s	−0.2666	−0.3258	− 0.1852	− 0.2889	−0.3184	−0.3184
Gender	P value	0.0737	0.3185	0.1149	0.0809	0.0809	0.0737
Smoking history (Pack-years)	r_s	−0.3670	− 0.3645	− 0.3568	− 0.3817	− 0.5333	− 0.4753
Smoking history (Pack-years)	P value	0.0423	0.0438	0.0488	0.0341	0.0020	0.0069
FEV₁ (% pred)	r_s	0.4140	0.3533	0.5115	0.4459	0.4656	0.3958
FEV₁ (% pred)	P value	0.0206	0.0512	0.0033	0.0119	0.0083	0.0275
Low attenuation area scores	r_s	−0.5358	−0.5577	−0.4564	−0.4945	−0.6778	−0.6440
Low attenuation area scores	P value	0.0019	0.0011	0.0099	0.0047	< 0.0001	< 0.0001

Bold denotes values P < 0.05

r_s, Spearman rank correlation coefficient. FEV₁, forced expiratory volume in 1 second. MFI, mean fluorescence intensity

MFI ratio indicates the ratio of receptor MFI to the corresponding FMO control MFI

% positive indicates the percentage of a receptor-positive alveolar macrophages to total alveolar macrophages