Table 2.

Occurrence of postoperative bleeding complications overall split into before and after start of anticoagulation, and summing up

	study population	heparin (H)	argatroban (A)	H vs. A p-value	switched (S)	H vs. S p-value
number	215 100% (215/215)	143 66.5% total (143/215)	43 20% total (43/215)		29 13.5% total (29/215)
postoperative bleeding complication before initiation of anticoagulation	14.4% (31/215)	7.7% group (11/143)	32.5% group (14/43)		20.7% group (6/29)
		5.1% total (11/215)	6.5% total (14/215)		2.8% total (6/215)
postoperative bleeding complication after initiation of anticoagulation	12.1% (26/215)	9.8% group (14/143)	14.0% group (6/43)	n.s. (0.413)	20.7% group (6/29)	n.s. (0.113)
		6.5% total (14/215)	2.8% total (6/215)		2.8% total (6/215)
postoperative bleeding complication total	26.5% (57/215)	17.5% group (25/143)	46.5% group (20/43)	< 0.001	41.4% group (12/29)	0.011
		11.6% total (25/215)	9.3% total (20/215)		5.6% total (12/215)

Values reaching significance are merked bold