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. 2020 Jan 28;20:28. doi: 10.1186/s12935-020-1109-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — P22077 inhibits HCC growth in xenograft mice. a P22077 inhibited growth of SK-Hep1 xenograft tumors. Xenograft tumors were generated by injecting SK-Hep1 cells with or without P22077 at dose of 10 mg/kg. b, c, the growth of xenograft tumors was moved and measured, the tumor weight was recorded. All *P < 0.05 was considered significant