Fig. 9.

Effects of FTO inhibitior FB23–2 on neurological functions and cognitive and learning abilities in TBI. a, the score of four groups in mNSS: TBI + FB23–2 (n = 7), TBI + DMSO (n = 8), Sham+FB23–2 (n = 5), and Sham+DMSO (n = 5). b and c, the escape latency time and target quadrant time of four groups in MWM, respectively: TBI + FB23–2 (n = 7), TBI + DMSO (n = 8), Sham+FB23–2 (n = 5), and Sham+DMSO (n = 5). “*”, “**”, and “***” indicate p < 0.05, p < 0.01, and p < 0.001 in TBI vs Sham, respectively; “#”, “##”, and “###” indicate p < 0.05, p < 0.01, and p < 0.001 in FB23–2 vs DMSO. Error bars represent SD. NS indicates p > 0.05