Multi-omic Pathway and Network Analysis to Identify Biomarkers for Hepatocellular Carcinoma

. Author manuscript; available in PMC: 2020 Jan 28.

Published in final edited form as: Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:1350–1354. doi: 10.1109/EMBC.2019.8856576

Serum molecules comprising the FXR RXR Activation Pathway

Serum Molecules
Metabolomics (GC-MS + LC-MS)	Glycoproteomics
Chenodeoxycholic acid (CID:10133)^*	Complement Component (C4A/C4B)^* (Uniprot:P0C0L4/P0C0L5)
Deoxycholate (CID:222528)^*	Hemopexin (HPX) (Uniprot:P02790)
D-glucose (CID:5793)^*	Kininogen-1 precursor (KNG1) (Uniprot:P01042)
xylitol (KEGG:D00061)	Apolipoprotein B (APOB) (Uniprot:P04114)
	Inter-alpha-trypsin Inhibitor Heavy Chain H4 (ITIH4) (Uniprot:Q14624)
	Complement Component C9 (C9) (Uniprot:P02748)
	Alpha-2-HS-Glycoprotein (AHSG) (Uniprot:P02765)
	Clusterin (CLU) (Uniprot:P10909)

Molecules with FDR<0.05