Fig. 3.

Stem cell population in the mouse incisor. In the labial cervical loop, Sox2+ epithelial stem cells are responsible for replenishing the enamel and epithelial tissue. Gli1+ and glial cells residing in the mesenchyme between the labial and lingual cervical loop regions close to the neurovascular bundle represent slow-cycling stem cells. Transit amplifying cells located either in the mesenchyme close to the labial and lingual cervical loop region or in the labial cervical loop are derived from self-renewing stem cells. NG2+ pericytes located on the abluminal surface of endothelial cells contribute to mesenchymal tissue repair after injury.