Table 5.
No LPS | LPS | P-values | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Item2,3 | CON | CON-B | DON | DON-B | CON | CON-B | DON | DON-B | SEM | DON | B | LPS | DON × B | DON × LPS | B × LPS | DON × B × LPS |
α-diversity metrices | ||||||||||||||||
Shannon | 6.15 | 6.43 | 6.24 | 6.30 | 6.34 | 6.40 | 6.18 | 6.18 | 0.118 | 0.217 | 0.236 | 0.960 | 0.418 | 0.297 | 0.387 | 0.646 |
Simpson | 0.94 | 0.96 | 0.95 | 0.95 | 0.96 | 0.96 | 0.95 | 0.95 | 0.012 | 0.648 | 0.248 | 0.331 | 0.697 | 0.712 | 0.378 | 0.733 |
Chao1 | 1517 | 1417 | 1384 | 1488 | 1411 | 1450 | 1345 | 1389 | 67.527 | 0.325 | 0.654 | 0.272 | 0.278 | 0.730 | 0.684 | 0.303 |
Family | ||||||||||||||||
f_Lachnospiraceae | 31.7 | 34.8 | 32.1 | 29.2 | 33.5 | 31.6 | 29.7 | 33.1 | 1.598 | 0.102 | 0.715 | 0.985 | 0.878 | 0.495 | 0.770 | 0.015 |
f_Ruminococcaceae | 16.9 | 17.3 | 14.3 | 16.2 | 17.7 | 16.4 | 15.2 | 14.2 | 0.866 | 0.001 | 0.942 | 0.616 | 0.466 | 0.648 | 0.066 | 0.668 |
f_Bacteroidaceae | 13.0 | 6.0 | 12.8 | 10.5 | 8.8 | 10.7 | 10.4 | 9.3 | 1.997 | 0.427 | 0.138 | 0.570 | 0.763 | 0.489 | 0.081 | 0.171 |
f_Lactobacillaceae | 5.9 | 6.7 | 5.5 | 6.5 | 4.5 | 5.2 | 7.8 | 7.4 | 1.118 | 0.127 | 0.493 | 0.939 | 0.768 | 0.065 | 0.638 | 0.666 |
f_Turicibacteraceae | 0.53 | 0.73 | 0.51 | 0.34 | 0.85 | 0.31 | 0.58 | 0.63 | 0.181 | 0.486 | 0.362 | 0.609 | 0.654 | 0.369 | 0.315 | 0.063 |
f_Coriobacteriaceae | 0.23 | 0.28 | 0.17 | 0.21 | 0.26 | 0.22 | 0.19 | 0.24 | 0.031 | 0.064 | 0.292 | 0.706 | 0.389 | 0.365 | 0.402 | 0.208 |
f_Bifidobacteriaceae | 0.094 | 0.18 | 0.072 | 0.067 | 0.30 | 0.31 | 0.13 | 0.13 | 0.088 | 0.056 | 0.712 | 0.066 | 0.698 | 0.375 | 0.800 | 0.764 |
f_Peptostreptococcaceae | 0.064 | 0.084 | 0.064 | 0.083 | 0.095 | 0.075 | 0.11 | 0.070 | 0.022 | 0.833 | 0.706 | 0.343 | 0.688 | 0.811 | 0.096 | 0.717 |
f_[Mogibacteriaceae] | 0.049 | 0.037 | 0.042 | 0.033 | 0.039 | 0.042 | 0.037 | 0.038 | 0.005 | 0.176 | 0.219 | 0.716 | 0.953 | 0.759 | 0.071 | 0.725 |
f_Leuconostocaceae | 0.009 | 0.058 | 0.037 | 0.017 | 0.031 | 0.032 | 0.033 | 0.035 | 0.012 | 0.811 | 0.363 | 0.762 | 0.057 | 0.597 | 0.449 | 0.042 |
o_RF39 | 0.020 | 0.024 | 0.009 | 0.018 | 0.012 | 0.043 | 0.002 | 0.008 | 0.013 | 0.096 | 0.179 | 0.873 | 0.591 | 0.441 | 0.567 | 0.423 |
Genus | ||||||||||||||||
g_[Ruminococcus] | 12.8 | 16.2 | 13.5 | 11.8 | 14.7 | 12.8 | 11.5 | 13.2 | 1.167 | 0.050 | 0.637 | 0.513 | 0.630 | 0.797 | 0.548 | 0.011 |
g_Bacteroides | 13.0 | 6.0 | 12.8 | 10.5 | 8.8 | 10.7 | 10.4 | 9.3 | 1.997 | 0.427 | 0.138 | 0.570 | 0.763 | 0.489 | 0.081 | 0.171 |
f_Ruminococcaceae1 | 7.8 | 8.3 | 6.3 | 8.1 | 9.0 | 8.2 | 6.6 | 6.7 | 0.646 | 0.003 | 0.368 | 0.998 | 0.260 | 0.236 | 0.113 | 0.838 |
g_Lactobacillus | 5.9 | 6.7 | 5.5 | 6.5 | 4.5 | 5.2 | 7.8 | 7.4 | 1.118 | 0.127 | 0.493 | 0.939 | 0.768 | 0.065 | 0.638 | 0.666 |
g_Oscillospira | 5.2 | 5.1 | 4.6 | 4.9 | 5.0 | 5.0 | 5.0 | 4.1 | 0.317 | 0.054 | 0.390 | 0.458 | 0.644 | 0.844 | 0.204 | 0.135 |
g_Ruminococcus | 3.6 | 3.8 | 3.2 | 3.0 | 3.4 | 3.0 | 3.4 | 3.3 | 0.270 | 0.214 | 0.503 | 0.507 | 0.909 | 0.068 | 0.462 | 0.405 |
g_Dorea | 1.3 | 1.7 | 1.4 | 1.3 | 1.7 | 1.7 | 1.2 | 1.1 | 0.191 | 0.013 | 0.930 | 0.861 | 0.248 | 0.134 | 0.380 | 0.547 |
f_Lachnospiraceae2 | 0.70 | 0.62 | 0.68 | 0.57 | 0.59 | 0.55 | 0.48 | 0.64 | 0.058 | 0.567 | 0.736 | 0.062 | 0.333 | 0.818 | 0.061 | 0.184 |
g_Turicibacter | 0.53 | 0.73 | 0.51 | 0.34 | 0.85 | 0.31 | 0.58 | 0.63 | 0.181 | 0.486 | 0.362 | 0.609 | 0.654 | 0.369 | 0.315 | 0.063 |
g_Coprobacillus | 0.42 | 0.36 | 0.59 | 0.50 | 0.40 | 0.44 | 0.50 | 0.52 | 0.085 | 0.042 | 0.715 | 0.966 | 0.816 | 0.636 | 0.414 | 0.991 |
g_Clostridium | 0.39 | 0.20 | 0.41 | 0.20 | 0.25 | 0.11 | 0.24 | 0.22 | 0.110 | 0.715 | 0.073 | 0.227 | 0.756 | 0.811 | 0.442 | 0.684 |
g_Eggerthella | 0.17 | 0.22 | 0.13 | 0.16 | 0.20 | 0.15 | 0.15 | 0.19 | 0.027 | 0.097 | 0.392 | 0.883 | 0.383 | 0.254 | 0.245 | 0.124 |
g_Bifidobacterium | 0.094 | 0.18 | 0.072 | 0.067 | 0.30 | 0.31 | 0.13 | 0.13 | 0.088 | 0.056 | 0.712 | 0.066 | 0.698 | 0.375 | 0.800 | 0.764 |
f_Erysipelotrichaceae1 | 0.12 | 0.19 | 0.16 | 0.049 | 0.17 | 0.12 | 0.070 | 0.098 | 0.049 | 0.143 | 0.648 | 0.654 | 0.429 | 0.837 | 0.854 | 0.065 |
f_Peptostreptococcaceae1 | 0.063 | 0.084 | 0.063 | 0.083 | 0.094 | 0.074 | 0.11 | 0.069 | 0.022 | 0.827 | 0.713 | 0.353 | 0.682 | 0.808 | 0.099 | 0.711 |
f_Ruminococcaceae2 | 0.097 | 0.090 | 0.068 | 0.091 | 0.086 | 0.065 | 0.079 | 0.052 | 0.011 | 0.131 | 0.311 | 0.042 | 0.444 | 0.825 | 0.044 | 0.260 |
f_[Mogibacteriaceae] 1 | 0.049 | 0.037 | 0.042 | 0.033 | 0.039 | 0.042 | 0.037 | 0.038 | 0.005 | 0.176 | 0.219 | 0.716 | 0.953 | 0.759 | 0.071 | 0.725 |
f_Leuconostocaceae1 | 0.009 | 0.058 | 0.037 | 0.017 | 0.031 | 0.032 | 0.033 | 0.035 | 0.012 | 0.811 | 0.363 | 0.762 | 0.057 | 0.597 | 0.449 | 0.042 |
o_RF391 | 0.020 | 0.024 | 0.009 | 0.018 | 0.012 | 0.043 | 0.002 | 0.008 | 0.013 | 0.096 | 0.179 | 0.873 | 0.591 | 0.441 | 0.567 | 0.423 |
1CON, control diet. Values are least square means and pooled SEM; n = 10.
2Rarefaction depth of 10,000 sequences to determine α-diversity.
3Differently abundant bacterial families and genera with a relative abundance >0.01%.