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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Cancer Metastasis Rev. 2019 Sep;38(3):493–506. doi: 10.1007/s10555-019-09814-4

Fig. 3. Ingenuity Pathway Analysis (IPA) for KISS1-regulated network.

Fig. 3

KISS1-regulated network is associated with proteins, ions, RNA molecules and chemical compounds. KISS1 is positioned in the center of the protein network. The interacting proteins are depicted as various geometric shapes, each representing a particular functional class of proteins, whereas their position with regard to two horizontal solid lines reflects their compartmentalization properties/ intracellular localization, i.e. in the nucleus, cytoplasm or extracellular space. Proteins with unknown localization are positioned inside the vertical box on the right (“unknown”). The length and type of each protein-connecting line reflects either predicted (dashed line) or experimentally evidenced/published (solid line) interactions. Data were analyzed through the use of IPA (Ingenuity® Systems, http://www.ingenuity.com).