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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Immunol Rev. 2019 Dec 16;293(1):8–24. doi: 10.1111/imr.12830

Figure 1.

Figure 1.

Changes in the PI3K-Akt pathway in monocytes during acute malaria. Negatively selected monocytes were obtained from Kenyan children at presentation with acute uncomplicated malaria and 6 weeks following treatment (n = 6). RNA and protein were purified from monocyte cell lysates and hybridized to a NanoString CodeSet of genes and proteins important to regulation of several cellular processes such as differentiation, apoptosis, and metabolism (mRNA PanCancer Pathways Panel of 730 target genes and protein Solid Tumor Panel of 25 total and phospho-proteins). PTEN = phosphatase and tensin homolog, PPP2CB = protein phosphatase 2 catalytic subunit beta, CCND3 = cyclin D3.