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. 2020 Jan 23;15:483–495. doi: 10.2147/IJN.S229858

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© 2020 Yu et al.

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pDNA@SNP^x/y preparation and evaluation. (A). Scheme of pDNA@SNP^x/y preparation. (B). Gel retardation assay of pGL3@SNPs^x/y. (C). Hydrodynamic size (column diagram) and zeta potentials (broken line diagram) of pGL3@SNPs^x/y obtained from DLS measurement. (D). Activity of luciferase expressed by Jurkat cells transfected with pGL3@SNPs^x/y (*P<0.05, **P>0.05).

Abbreviations: pDNA, plasmid DNA; Ad-PEG, adamantane-grafted poly(ethylene glycol) (molecular weight: 5000); Ad-PAMAM^x, adamantane-grafted polyamidoamine dendrimer (x: PAMAM dendrimer generation); CD-PEI^y, cyclodextrin-grafted branched polyethylenimine (y: PEI molecular weight); SNPs, self-assembled nanoparticles; DLS, dynamic light scattering.