. Author manuscript; available in PMC: 2020 Jan 28.

Published in final edited form as: Adv Protein Chem Struct Biol. 2019 Jan 3;116:397–419. doi: 10.1016/bs.apcsb.2018.11.011

Table 2.

Databases and software tools for modeling GPCR-G protein interactions

Database/Software	Description	Reference and website
PDB	A database contains biological macromolecular structures determined by experiments.	(Berman et al., 2000) https://www.rcsb.org/
GPCRdb	A database contains structures, diagrams and web tools of GPCRs.	(Munk et al., 2016) http://gpcrdb.org/
gpPDB	A database contains information about GPCRs, effectors of GPCRs and their known interactions.	(Theodoropoulou et al., 2008) http://bioinformatics.biol.uoa.gr/gpDB/
Human gpDB	A database contains information about 713 human GPCRs, 36 human G-proteins and 99 human effectors.	(Satagopam et al., 2010) http://bioinformatics.biol.uoa.gr/human_gpdb/
OMP	A database provides information about structural classification of membrane proteins, topology, spatial positions in the lipid bilayer, and intracellular localization.	(Lomize, Pogozheva, Joo, Mosberg, & Lomize, 2012) https://opm.phar.umich.edu/
CHARMM-GUI	A web-based graphical user interface that helps preparation of biomolecular systems (including GPCRs and the G proteins) for molecular dynamics simulations.	(Jo et al., 2017) http://www.charmm-gui.org/