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. 2020 Jan 28;15(1):e0228212. doi: 10.1371/journal.pone.0228212

Fig 8. Effects of GS-0976 on hepatic mRNA expression.

Fig 8

Gene expressions of (A) collagen1 α1 (Col1a1), (B) collagen1 α2 (Col1a2), (C) Transforming growth factor β1 (TGFβ1) and (D) F4/80. The liver was harvested one hour after the last administration of the 9-week treatment. Gene expressions were measured in the liver homogenates. Data are represented as the mean + SD, **p<0.01 vs. MC4R KO mice treated with vehicle by Aspin-Welch test, #p<0.025, ##p<0.005 vs. MC4R KO mice treated with vehicle by one-tailed Williams’ test or Shirley-Williams test.