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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Adv Mater. 2019 Nov 29;32(2):e1903285. doi: 10.1002/adma.201903285

Figure 8. D4 immunoassay performance on zwitterionic polymer brush surfaces.

Figure 8.

D4 assay dose-response curves for IL-6 Ag on (A) POEGMA and (B) PSBMA polymer brush surfaces. The PSBMA surface is too hydrophilic to allow inkjet printing immobilization of Ab reagents, resulting in no visible dose-response behavior in panel B. C) Optical images and quantification of contact angles for POEGMA and PSBMA brushes, showing the significantly lower water contact angle on the zwitterionic PSBMA surface. D) D4 assay dose-respose curves for IL-6 Ag on a poly-2-(dimethylamino)ethyl methacrylate (PDMAEMA) brush and a PDMAEMA polymer brush surface that was partially derivatized to PCBMA at 75 °C, pH 5. The assay metrics for the PCBMA surface are similar to the same assay on a POEGMA brush surface. Adapted with permission.[82] Copyright 2018, American Chemical Society.